Job Description

POSITION OBJECTIVE

Working under general supervision, the Research Assistant 2 will plan and carry out molecular and cell biology research projects in accordance with general plans. The lab uses functional genomics approaches to elucidate the molecular and cell biology of human epithelia and their dysfunction in disease states such as Cystic Fibrosis. Projects will build upon our single cell RNA-seq data on rare cell types and involve gene expression analysis and assays of protein function.

ESSENTIAL FUNCTIONS * Conduct state-of-the-art genomics technologies and functional assays including but not limited to gene expression assays; analysis of DNA, RNA and proteins; all related protocols of functional genomics including chromatin and RNA purification; analysis by deep sequencing and single cell sequencing and protocols of cell biology and biochemistry such as cell culture and protein analysis. (30%)

• May assist in developing improved techniques based on genomics technologies and functional assays, projection methods or procedures. (20%)
• Collect and analyze data using appropriate laboratory machines designed for performing cell biological, biochemical and molecular analysis. Data will involve images and numbers, which will be analyzed by appropriate statistical packages. (15%)
• Oversee supply inventory and ordering. Maintain chemical and biological inventories. Maintain certain equipment facilities including laboratory cell culture facility and functional genomics equipment room with advanced thermal cyclers for quantitative gene expression analysis, bioruptors etc. (10%)
• Train new staff; direct the work of students. Collaborate with faculty members and scientists for training in the performance and analysis of complex and advanced research studies. (10%)
• Maintain research related materials to include study data, publications, submitted grants and other scientific documents. Collaborate with scientists in the preparation of manuscripts. Maintain laboratory databases. (8%)

NONESSENTIAL FUNCTIONS * Participate in meetings to present research study findings. (5%)

• Perform other duties as assigned. (2%)

CONTACTS

Department: Daily contact with principal investigators, postdocs, research associates and research assistants to review reagent needs or organize research interactions between different research teams in the department.

University: Daily contact with principal investigators, postdocs, research associates, research assistants, graduate students outside department. The supervisor has many collaborations both internal to the university and elsewhere, which will be facilitated by the research assistant.

External: Limited contact with outside vendors to obtain quotes for reagents, organize maintenance of equipment or solve problems relating to ordering and invoicing.

Students: Daily contact with graduate students, undergraduates and fellows to facilitate their research and ensure an efficient work environment

SUPERVISORY RESPONSIBILITY

This position has no direct supervision of staff employees. Train new staff; direct the work of students.

QUALIFICATIONS

Education/Experience: Bachelor\'s degree and 1 to 3 years of related experience or Associate\'s degree in an approved biotechnology program and 2 to 4 years of experience required.

REQUIRED SKILLS * Prior experience in practical cell biology, genetics, molecular biology or functional genomics techniques and analysis is required, at minimum in undergraduate research setting.

• Prior bench work experience in an academic science or medicine setting and/or a clinical research setting in strongly preferred.
• Strong numeracy and data analysis skills.
• Computer proficiency in Microsoft Suite, Adobe Creative Suite, Graphpad an advantage.
• Strong oral and written communication skills.
• Strong organizational and management skills and ability to work in a fast paced environment.
• Ability to meet consistent attendance.
• Ability to interact with colleagues, supervisors and customers face to face.

WORKING CONDITIONS

The position entails working in a biomedical research laboratory. The employee will be expected to adhere to all required certification for laboratory work and adhere to all safety regulations including the use of personal protective equipment, standard lab coat, gloves and safety glasses when appropriate. The position may require extended hours including weekends as experiments dictate.

Diversity Statement

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.

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Reasonable Accommodations

Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

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COVID Vaccination

Case Western Reserve University has implemented a COVID Vaccination policy requiring evidence of COVID-19 vaccination for all students, faculty and staff with an on-campus presence. Religious and medical exemptions may be provided in accordance with applicable federal and state laws. For more information go to: https://case.edu/equity/covid-19-accommodations. Applicants may contact the Office of Equity at 216-368-3066 /equity@case.edu for information regarding religious or medical exemptions as an accommodation.

Case Western Reserve University